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Pomaglumetad methionil (hydrochloride)

Pomaglumetad methionil (hydrochloride)

Item no.	HY-105040C-5mg
Manufacturer	MedChem Express
CASRN	635318-26-2
Amount	5 mg
Quantity options	100 mg 10 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	98.0
Formula	C12H19ClN2O7S2
Citations	[1]Lowe S, et al. Effects of a novel mGlu<sub>₂/₃</sub> receptor agonist prodrug, LY2140023 monohydrate, on central monoamine turnover as determined in human and rat cerebrospinal fluid. Psychopharmacology (Berl). 2012 Feb;219(4):959-70.<br/>[2]Y Anne Pak, et al. In Vitro and Clinical Evaluations of the Drug-Drug Interaction Potential of a Metabotropic Glutamate 2/3 Receptor Agonist Prodrug with Intestinal Peptide Transporter 1. Drug Metab Dispos. 2017 Feb;45(2):137-144.
Smiles	CSCC[C@H](N)C(N[C@]([C@@]1([H])[C@](S2(=O)=O)([H])[C@@H]1C(O)=O)(C2)C(O)=O)=O.[H]Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	LY2140023 (hydrochloride)
Similar products	635318-26-2
Available
Product Description	Pomaglumetad methionil hydrochloride (LY2140023 hydrochloride) is an orally active, methionine prodrug of the selective mGlu2/3 receptor agonist LY404039. Pomaglumetad methionil hydrochloride has the potential for schizophrenia research[1][2].
StorageTemperature	4°C (Powder, stored under nitrogen)
Shipping	Room Temperature
Manufacturers Applications	Neuroscience-Neuromodulation
MolecularWeight	402.87
Clinical Information	Phase 3
Manufacturers Research Area	Neurological Disease
Solubility	DMSO : 25 mg/mL (ultrasonic)
Target	mGluR
Manufacturers Target	mGluR
Isoform	mGluR2; mGluR3
Manufacturers Pathway	GPCR/G Protein; Neuronal Signaling
Manufacturers Product type	Reference compound

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