ML402

Item no.	HY-104027-25mg
Manufacturer	MedChem Express
CASRN	298684-44-3
Amount	25 mg
Quantity options	100 mg 10mM/1mL 10 mg 1 mg 25 mg 50 mg 5mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.86
Formula	C14H14ClNO2S
Citations	[1]Lolicato M, et al. K2P2.1 (TREK-1)-activator complexes reveal a cryptic selectivity filter binding site. Nature. 2017 Jul 20;547(7663):364-368.
Smiles	O=C(C1=CC=CS1)NCCOC2=CC=C(Cl)C=C2C
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Product Description	ML402, a thiophene-carboxamide, is a selective K2P2.1(TREK-1) and K2P10.1(TREK-2) activator. ML402 is inactive against K2P4.1(TRAAK)[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Neuroscience-Neuromodulation
MolecularWeight	295.78
Clinical Information	No Development Reported
Manufacturers Research Area	Neurological Disease
Solubility	DMSO : ≥ 100 mg/mL
Target	Potassium Channel
Manufacturers Target	Potassium Channel
Manufacturers Pathway	Membrane Transporter/Ion Channel
Manufacturers Product type	Reference compound

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