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(R)-Zanubrutinib

(R)-Zanubrutinib

Item no.	HY-101474B-100mg
Manufacturer	MedChem Express
CASRN	1691249-44-1
Amount	100 mg
Quantity options	100 mg 10mM/1mL 10 mg 1mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	97.08
Formula	C27H29N5O3
Citations	[1]Wu J, et al. Acalabrutinib (ACP-196): a selective second-generation BTK inhibitor. J Hematol Oncol. 2016 Mar 9;9:21.<br/>[2]Wu J, et al. Second-generation inhibitors of Bruton tyrosine kinase. J Hematol Oncol. 2016 Sep 2;9(1):80.
Smiles	NC(C1=C2N(N=C1C3=CC=C(OC4=CC=CC=C4)C=C3)[C@@H](C5CCN(C(C=C)=O)CC5)CCN2)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	(R)-BGB-3111
Available
Product Description	(R)-Zanubrutinib is the R enantiomer of Zanubrutinib (HY-101474A). (R)-Zanubrutinib inhibits Bruton's tyrosine kinase (Btk) with an IC50 of 11 nM.
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
MolecularWeight	471.55
Clinical Information	No Development Reported
Manufacturers Research Area	Others
Solubility	DMSO : ≥ 64.25 mg/mL
Target	Btk
Manufacturers Target	Btk
Manufacturers Pathway	Protein Tyrosine Kinase/RTK
Manufacturers Product type	Reference compound

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