Comparison

HCH6-1 European Partner

Item no. HY-101283-50mg
Manufacturer MedChem Express
CASRN 1435265-06-7
Amount 50 mg
Quantity options 100 mg 10mM/1mL 10 mg 50 mg 5 mg
Category
Type Inhibitors
Specific against other
Purity 99.14
Formula C28H27N3O4
Citations [1]Yang SC, et al. Dipeptide HCH6-1 inhibits neutrophil activation and protects against acute lung injury by blocking FPR1. Free Radic Biol Med. 2017 May;106:254-269
Smiles O=C(N[C@H](C(N[C@@H](C(OC)=O)CC1=CC=CC=C1)=O)CC2=CNC3=C2C=CC=C3)C4=CC=CC=C4
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias 1435265-06-7
Available
Product Description
HCH6-1 is a potent and competitive dipeptide antagonist of Formyl peptide receptor 1 (FPR1). HCH6-1 inhibits chemotaxis, superoxide anion generation, and elastase release in human neutrophils specifically activated by fMLF (an FPR1 agonist). HCH6-1 has protective effects against acute lung injury (ALI) in vivo and can be used for the research of FPR1-involved inflammatory lung diseases[1].
StorageTemperature
-20°C, 3 years; 4°C, 2 years (Powder)
Shipping
Room Temperature
Manufacturers Applications
COVID-19-immunoregulation
MolecularWeight
469.53
Clinical Information
No Development Reported
Manufacturers Research Area
Inflammation/Immunology
Solubility
DMSO : 250 mg/mL (ultrasonic)
Target
Formyl Peptide Receptor (FPR)
Manufacturers Target
Formyl Peptide Receptor (FPR)
Manufacturers Pathway
GPCR/G Protein
Manufacturers Product type
Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 mg
Available: In stock
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