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VEGFR-IN-1

VEGFR-IN-1

Item no.	HY-101219-10mM
Manufacturer	MedChem Express
CASRN	269390-69-4
Amount	10mM/1mL
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	98.42
Formula	C19H16ClN3O
Citations	[1]Furet P, et al. Identification of a new chemical class of potent angiogenesis inhibitors based on conformational considerations and database searching. Bioorg Med Chem Lett. 2003;13(18):2967-2971.
Smiles	O=C(NC1=CC=C(Cl)C=C1)C2=CC=CC=C2NCC3=CC=NC=C3
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Product Description	VEGFR-IN-1 (compound 3) is a potent angiogenesis inhibitor with IC50s of 0.02, 0.18, 0.24 7.3, and 7 µM for KDR, Flt-1, c-Kit, EGF-R, and c-Src, respectively[1].
StorageTemperature	-20°C (Powder, protect from light, stored under nitrogen)
Shipping	Blue Ice
Manufacturers Applications	Cancer-Kinase/protease
MolecularWeight	337.80
Clinical_Information	No Development Reported
Manufacturers Research_Area	Cancer
Solubility	DMSO : 125 mg/mL (ultrasonic)
Isoform	EGFR/ErbB1/HER1; VEGFR1/Flt-1; VEGFR2/KDR/Flk-1
Pathway	JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Manufacturers Product type	Reference compound

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