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RS 23597-190

RS 23597-190

Item no.	HY-101172-1ea
Manufacturer	MedChem Express
CASRN	149719-06-2
Amount	1 ea
Quantity options	100 mg 10 mg 1 ea 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Purity	99.06
Formula	C16H24Cl2N2O3
Citations	[1]Eglen RM, et al. RS 23597-190: a potent and selective 5-HT4 receptor antagonist. Br J Pharmacol. 1993 Sep;110(1):119-26. [2]Du Y, et al. Adrenergic and serotonin receptors affect retinal superoxide generation in diabetic mice: relationship to capillary degeneration and permeability. FASEB J. 2015 May;29(5):2194-204.
Smiles	O=C(OCCCN1CCCCC1)C2=CC(Cl)=C(N)C=C2OC.Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	EP-A-501322
Shipping condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Neuroscience-Neuromodulation
Manufacturer - Targets	5-HT Receptor
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, sealed storage, away from moisture)
Molecular Weight	363.28
Product Description	RS 23597-190 (EP-A-501322) is a high affinity and selective 5-HT4 receptor antagonist. RS 23597-190 inhibits 5-HT (HY-B1473A)-induced tachycardia. RS 23597-190 significantly inhibits superoxide production in high glucose[1][2].
Manufacturer - Research Area	Cardiovascular Disease
Solubility	H2O : 5 mg/mL (ultrasonic; warming)\|DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturer - Pathway	GPCR/G Protein; Neuronal Signaling
Isoform	5-HT4 Receptor
Clinical information	No Development Reported

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HY-101172-1ea-safety-datasheet.pdf