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Saclofen

Saclofen

Item no.	HY-100813-5mg
Manufacturer	MedChem Express
CASRN	125464-42-8
Amount	5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Purity	99.87
Formula	C9H12ClNO3S
Citations	[1]Sallam MY, et al. Central GABAA receptors are involved in inflammatory and cardiovascular consequences of endotoxemia in conscious rats. Naunyn Schmiedebergs Arch Pharmacol. 2016 Mar;389(3):279-88.
Smiles	O=S(CC(CN)C1=CC=C(Cl)C=C1)(O)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Product Description	Saclofen is a competitive antagonist of the GABAB receptor with an IC50 of 7.8 μM. Saclofen can be used to determine the functional roles for the GABAB receptor as a mediator of slow inhibitory postsynaptic potentials in the brain[1].
StorageTemperature	-20°C, 3 years (Powder)
Shipping	Blue Ice
Manufacturers Applications	Neuroscience-Neuromodulation
MolecularWeight	249.71
Clinical_Information	No Development Reported
Manufacturers Research_Area	Neurological Disease
Solubility	H2O : 10 mg/mL (ultrasonic)
Manufacturers Target	GABA Receptor
Pathway	Membrane Transporter/Ion Channel; Neuronal Signaling
Manufacturers Product type	Reference compound

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HY-100813-5mg-safety-datasheet.pdf