FM26

Item no.	DCC-DC28745-1g
Manufacturer	DCChemicals
CASRN	2407981-35-3
Amount	1 g
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Smiles	C1C=C(C=CC=1C(=O)O)NCC1C(C2C(Cl)=CC=CC=2C(F)(F)F)=NOC=1C1=CNC=C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Molecule Weight	461, 82
Field of Application	FM26 (compound 25) is a potent and allosteric retinoic acid receptor-related orphan receptor γt (RORγt) inverse agonists with an IC50 of 264 nM. FM26 has a distinct isoxazole chemotype and effectively reduces IL-17a mRNA production in EL4 cells.

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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