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ACVR2A/Activin RIIA, Human (HEK293, Fc)

ACVR2A/Activin RIIA, Human (HEK293, Fc)

Item no.	HY-P75537-50ug
Manufacturer	MedChem Express
Amount	50 ug
Quantity options	1 ea 100 ug 10 ug 1 mg 200 ug 2 ug 500 ug 50 ug
Category	Inhibitors & Compound Libraries Compound Libraries
Type	Peptides
Specific against	other
Purity	96.00
Citations	[1]Oddrun Elise Olsen, et al. Activin A inhibits BMP-signaling by binding ACVR2A and ACVR2B. Cell Commun Signal. 2015 Jun 6;13:27. [2]V K Chin, et al. Inhibition of Activin A suppressed tumor necrosis factor-α secretion and improved histopathological conditions in malarial mice. Trop Biomed. 2021 Mar 1;38(1):187-204. [3]Szabina Szófia Szilágyi, et al. Competition between type I activin and BMP receptors for binding to ACVR2A regulates signaling to distinct Smad pathways. BMC Biol. 2022 Feb 18;20(1):50. [4]Heather L Hayes, et al. A Pdx-1-Regulated Soluble Factor Activates Rat and Human Islet Cell Proliferation. Mol Cell Biol. 2016 Nov 14;36(23):2918-2930.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	ACVR2A/Activin RIIA Protein, Human (HEK293, Fc),Human,HEK293
Shipping condition	Cool pack
Available
Shipping Temperature	Blue Ice
Molecular Weight	Approximately 55-70kDa due to the glycosylation.
Product Description	ACVR2A, also known as Activin RIIA, is an activin type II receptor. On ligand binding, ACVR2A can forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. ACVR2A is a receptor for Activin A, Activin B and Inhibin A[1][2]. ACVR2A/Activin RIIA Protein, Human (HEK293, Fc) is produced in HEK293 cells with a C-Terminal Fc-tag. It consists of 134 amino acids (M1-P134).

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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