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Cynomolgus/Rhesus macaque IL-31 RA Protein, Fc Tag

Cynomolgus/Rhesus macaque IL-31 RA Protein, Fc Tag

Item no.	ILA-H525b-1mg
Manufacturer	ACROBiosystems
Amount	1 mg
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Powder
Specific against	Monkey, Rhesus macaque
Host	HEK293
Conjugate/Tag	Unconjugated, Fc
Purity	90%
Formula	PBS, pH7.4
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Manufacturers Category	Protein / Bio-Markers & CD Antigens
Description	Cynomolgus/Rhesus macaque IL-31 RA Protein, Fc Tag (ILA-H525b) is expressed from human 293 cells (HEK293). It contains AA Ala 20 - Glu 519 (Accession # XP_005556977.2).
Molecule	IL-31 RA
Exp Region	Ala 20 - Glu 519
Storage	-20℃
Shipping	RT
Stability	-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Molecular Weight	84.5 kDa
Characteristics	This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 84.5 kDa. The protein migrates as 110-140 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	PBS, pH7.4
Background	Interleukin-31 receptor subunit alpha is a protein that in humans is encoded by the IL31RA gene, also known as IL-31 receptor subunit alpha, IL-31RA, GLM-R, Gp130-like receptor, CRL3, GPL. Oncostatin M receptor (OSMR) and IL31RA form the heterodimeric receptor through which IL31 signals. IL31RA is a strong activator of STAT3 and STAT5, whereas STAT1 is only marginally tyrosine-phosphorylated. dditionally, demonstrate Jak1 binding to GPL and its activation in heteromeric complexes with the OSMRbeta but also in a homomeric receptor complex.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1 mg

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Delivery expected until 8/16/2024

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