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O-Phospho-L-serine

O-Phospho-L-serine

Item no.	HY-15129-50mg
Manufacturer	MedChem Express
CASRN	407-41-0
Amount	50 mg
Quantity options	100 mg 10 mM/1 mL 50 mg
Specific against	other
Purity	98.0
Citations	[1]Kang HJ, et al. Determinants of endogenous ligand specificity divergence among metabotropic glutamate receptors. J Biol Chem. 2015 Jan 30;290(5):2870-8. [2]Kang HJ, et al. Selectivity and evolutionary divergence of metabotropic glutamate receptors for endogenous ligands and G proteins coupled to phospholipase C or TRP channels. J Biol Chem. 2014 Oct 24;289(43):29961-74. [3]Bailey TJ, et al. The inhibitor of phagocytosis, O-phospho-L-serine, suppresses Müller glia proliferation and cone cell regeneration in the light-damaged zebrafish retina. Exp Eye Res. 2010 Nov;91(5):601-12.
Smiles	OP(OC[C@@H](C(O)=O)N)(O)=O
Alias	L-Serine O-phosphate, L-SOP
Shipping condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	Neuroscience-Neuromodulation
Manufacturer - Targets	Endogenous Metabolite; mGluR
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	185.07
Product Description	O-Phospho-L-serine is the immediate precursor to L-cystein in the serine synthesis pathway, and an agonist at the group III mGluR receptors (mGluR4, mGluR6, mGluR7, and mGluR8); O-Phospho-L-serine also acts as a weak antagonist for mGluR1 and a potent antagonist for mGluR2[1].
Manufacturer - Research Area	Neurological Disease
Solubility	DMSO : < 1 mg/mL\|H2O : 25 mg/mL (ultrasonic)
Manufacturer - Pathway	GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling
Isoform	Human Endogenous Metabolite; mGluR1; mGluR2; mGluR4; mGluR6; mGluR7; mGluR8
Clinical information	No Development Reported

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HY-15129-50mg-safety-datasheet.pdf