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Cavidine

Cavidine

Item no.	HY-101546A-5mg
Manufacturer	MedChem Express
CASRN	32728-75-9
Amount	5 mg
Quantity options	1 ea 5 mg
Category	Inhibitors & Compound Libraries Compound Libraries
Type	Molecules
Specific against	other
Citations	[1]Niu X, et, al. Anti-inflammatory effects of cavidine in vitro and in vivo, a selective COX-2 inhibitor in LPS-induced peritoneal macrophages of mouse. Inflammation. 2015 Apr;38(2):923-33. [2]Niu X, et, al. Protective effect of cavidine on acetic acid-induced murine colitis via regulating antioxidant, cytokine profile and NF-κB signal transduction pathways. Chem Biol Interact. 2015 Sep 5:239:34-45. [3]Niu X, et, al. Cavidine Ameliorates Lipopolysaccharide-Induced Acute Lung Injury via NF-κB Signaling Pathway in vivo and in vitro. Inflammation. 2017 Aug;40(4):1111-1122.
Smiles	C[C@H]1C(C=C2)=C(C3=C2OCO3)CN4CCC5=CC(OC)=C(OC)C=C5[C@@]14[H]
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	(+)-Cavidine
Shipping condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	COX
Shipping Temperature	Room Temperature
Molecular Weight	353.41
Product Description	Cavidine ((+)-Cavidine) is a selective COX-2 inhibitor which possesses anti-inflammatory activity. Cavidine can be used for the research of skin injuries, hepatitis, cholecystitis, and scabies. Cavidine ameliorates LPS (HY-D1056)-induced acute lung injury via NF-κB signaling pathway[1][2][3].
Manufacturer - Research Area	Inflammation/Immunology
Solubility	10 mM in DMSO
Manufacturer - Pathway	Immunology/Inflammation
Clinical information	No Development Reported

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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