« Back
Home /
PNU-74654

PNU-74654

Item no.	HY-101130-1mg
Manufacturer	MedChem Express
Amount	1 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 1 mg 200 mg 25 mg 50 mg 5 mg
Specific against	other
Purity	99.93
Citations	[1]Leal LF, et al. Inhibition of the Tcf/beta-catenin complex increases apoptosis and impairs adrenocortical tumor cell proliferation and adrenal steroidogenesis. Oncotarget. 2015 Dec 15;6(40):43016-32. [2]Trosset JY, et al. Inhibition of protein-protein interactions: the discovery of druglike beta-catenin inhibitors by combining virtual and biophysical screening. Proteins. 2006 Jul 1;64(1):60-7.
Smiles	O=C(N/N=C/C1=CC=C(C)O1)C2=CC=CC=C2OC3=CC=CC=C3
Available
Product Description	PNU-74654 is an inhibitor of Wnt/β-catenin pathway with an IC50 of 129.8 μM in NCI-H295 cell.
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Applications	Cancer-programmed cell death
Molecular Weight	320.34
Clinical Information	No Development Reported
Manufacturer - Research Area	Cancer
Solubility	DMSO : ≥ 30 mg/mL
Target	Apoptosis; Wnt; β-catenin
Pathway	Apoptosis; Stem Cell/Wnt
Manufacturer - Category	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

HY-101130-1mg-safety-datasheet.pdf