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Fmoc-leucine

Fmoc-leucine

Item no.	HY-101064-50g
Manufacturer	MedChem Express
CASRN	35661-60-0
Amount	50 g
Quantity options	100 g 10 mM/1 mL 25 g 50 g 5 g
Specific against	other
Purity	99.91
Citations	[1]Rocchi S, et al. A unique PPARgamma ligand with potent insulin-sensitizing yet weak adipogenic activity. Mol Cell. 2001 Oct;8(4):737-47.
Smiles	CC(C)C[C@@H](C(O)=O)NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O
Alias	N-FMOC-leucine, NPC 15199, NSC 334290
Shipping condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Metabolism-sugar/lipid metabolism
Manufacturer - Targets	PPAR
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	353.418
Product Description	Fmoc-leucine is a selective PPARγ modulator. Fmoc-leucine activates PPARγ with a lower potency but a similar maximal efficacy than rosiglitazone. Fmoc-leucine improves insulin sensitivity in normal, diet-induced glucose-intolerant, and in diabetic db/db mice. Fmoc-leucine has a lower adipogenic activity[1].
Manufacturer - Research Area	Metabolic Disease
Solubility	DMSO : 50 mg/mL (ultrasonic)
Manufacturer - Pathway	Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Isoform	PPARγ
Clinical information	Phase 2

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HY-101064-50g-safety-datasheet.pdf