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cis-ACBD

cis-ACBD

Item no.	HY-100616-2mg
Manufacturer	MedChem Express
CASRN	73550-55-7
Amount	2 mg
Quantity options	100 mg 1 ea 2 mg
Category	Inhibitors & Compound Libraries Compound Libraries
Specific against	other
Citations	[1]Ai J, et al. Presynaptic excitability as a potential target for the treatment of the traumatic cerebellum. Pharmacology. 2004 Aug;71(4):192-8. [2]Griffiths R, et al. L-trans-pyrrolidine-2,4-dicarboxylate and cis-1-aminocyclobutane-1,3-dicarboxylate behave as transportable, competitive inhibitors of the high-affinity glutamate transporters. Biochem Pharmacol. 1994 Jan 20;47(2):267-74.
Smiles	OC([C@]1(C[C@@H](C1)C(O)=O)N)=O
Alias	cis-1-Aminocyclobutane-1,3-dicarboxylic acid
Shipping condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Neuroscience-Neuromodulation
Manufacturer - Targets	Others
Shipping Temperature	Room Temperature
Product Description	cis-ACBD is a potent and selective inhibitor of the high-affinity, Na+-dependent plasma membrane glutamate transporter. cis-ACBD is a glutamate reuptake inhibitor. cis-ACBD also acts as linear competitive inhibitor of the uptake of D-[3H]aspartate[1][2].
Manufacturer - Research Area	Neurological Disease
Solubility	10 mM in DMSO
Manufacturer - Pathway	Others
Clinical information	No Development Reported

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