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Neuron Specific Enolase (NSE)

Neuron Specific Enolase (NSE)

Item no.	11-511-248704
Manufacturer	GENWAY
Amount	1mg
Category	Oncology Peptides & Proteins Recombinant Proteins Western Blot ELISA By Organ Lung Cancer
Type	Proteins
Applications	WB, ELISA
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	GWB-50534F
Similar products	11-511-248704
Available
Genway ID:	GWB-50534F
Specificity:	Neuron Specific Enolase (NSE)
Type of Product:	Purified Neuroscience Reagents
Inactivation:	Not applicable
Buffer:	0. 1M Tris-HCl 5mM Mg2SO4 0. 25M KCl pH 5. 1Applications Notes : Tested in ELISA and immunoblotting with anti-NSE antibodies. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Concentration:	Concentration is lot specific Neuron Specific Enolase (NSE). . Subunit composition is gamma-gamma
Function:	Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds in a calcium-dependent manner to cultured neocortical neurons and promotes cell survival (By similarity).
Catalytic Activity:	2-phospho-D-glycerate = phosphoenolpyruvate + H2O. Cofactor: Magnesium. Required for catalysis and for stabilizing the dimer.
Pathway:	Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5.
Subunit:	Mammalian enolase is composed of 3 isozyme subunits alpha beta and gamma which can form homodimers or heterodimers which are cell-type and development-specific.
Subcellular Location:	Cytoplasm (By similarity). Cell membrane (By similarity). Note=Can translocate to the plasma membrane in either the homodimeric (alpha/alpha) or heterodimeric (alpha/gamma) form (By similarity).
Tissue Specificity:	The alpha/alpha homodimer is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons. Developmental Stage: During ontogenesis there is a transition from the alpha/alpha homodimer to the alpha/beta heterodimer in striated muscle cells and to the alpha/gamma heterodimer in nerve cells.
Induction:	Levels of ENO2 increase dramatically in cardiovascular accidents cerebral trauma brain tumors and Creutzfeldt-Jacob disease.
Similarity:	Belongs to the enolase family.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1mg

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Delivery expected until 8/30/2024

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