Comparison

Human EGF R - FcA Chimera

Item no. 10-006-220013-0,025mg
Manufacturer GENWAY
Amount 0,025 mg
Type Proteins
Specific against Human
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias GWB-1C8287
Similar products 10-006-220013
Available
Genway ID:
GWB-1C8287
Sequence:
LEEKKVCQGT SNKLTQLGTF EDHFLSLQRM FNNCEVVLGN LEITYVQRNY DLSFLKTIQE VAGYVLIALN TVERIPLENL QIIRGNMYYE NSYALAVLSN YDANKTGLKE LPMRNLQEIL HGAVRFSNNP ALCNVESIQW RDIVSSDFLS NMSMDFQNHL GSCQKCDPSC PNGSCWGAGE ENCQKLTKII CAQQCSGRCR GKSPSDCCHN QCAAGCTGPR ESDCLVCRKF RDEATCKDTC PPLMLYNPTT YQMDV
Activity:
The ED50 of EGF R - FcB Chimera is typically 60 -100 ng/ml as measured by its ability to neutralize EGF mediated proliferation of murine NIH3T3 fribroblasts. % Carbohydrate: purified EGF R - FcB Chimera consists of 5-30% carbohydrate by weight. Glycosylation: EGF R - FcB Chimera contains N- and O-linked oligosaccharides.
Reconstitution: It is recommended that 0. 5 ml of sterile phosphate-buffered saline be added to the vial. EGF R also known as Epidermal growth factor receptor is a member of the ErbB family receptors. EGF R is present in most if not all normal human epithelial cells. EGF R main function is as a receptor for EGF but it also acts as a receptor for other members of the EGF family such as TGF-alpha amphiregulin and heparin-binding EGF-like growth factor. When EGF attaches to human EGF R it activates the enzyme tyrosine kinase triggering reactions that cause the cells to grow and multiply. EGF R is a 479 amino acid glycoprotein that consists of an extracellular receptor domain a transmembrane region and an intracellular domain with tyrosine kinase function. N/AN/A [1] Callaghan T. Antczak M. Flickinger T. Raines M. Myers M. and Kung H. J. A complete description of the EGF-receptor exon structure: implication in oncogenic activation and domain evolution

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 0,025 mg
Available: In stock
available

Compare

Add to wishlist

Get an offer

Request delivery time

Ask a technical question

Submit a bulk request

Questions about this Product?
 
Close