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ATF2 (Phospho-Thr69 or 51) Antibody Blocking Peptide

ATF2 (Phospho-Thr69 or 51) Antibody Blocking Peptide

Manufacturer	GENWAY
Category	Oncology Peptides & Proteins Peptides By Organ Bladder Cancer
Type	Peptides
Specific against	other
Amount	0.1 mg
Item no.	06-785-213029
eClass 6.1	34160400
eClass 9.0	32160409
Available
Alias	GWB-E5F756
Genway ID:	GWB-E5F756
Function:	Transcriptional activator probably constitutive which binds to the cAMP-responsive element (CRE) (consensus: 5\' -GTGACGT[AC][AG]-3\' ) a sequence present in many viral and cellular promoters. Interaction with JUN redirects JUN to bind to CRES preferentially over the 12-O-tetradecanoylphorbol-13-acetate response elements (TRES) as part of an ATF2-c-Jun complex.
Subunit:	Binds DNA as a dimer and can form a homodimer in the absence of DNA. Can form a heterodimer with JUN. Interacts with SMAD3 and SMAD4. Binds through its N-terminal region to UTF1 which acts as a coactivator of ATF2 transcriptional activity.
Subcellular Location:	Nucleus.
Tissue Specificity:	Abundant expression seen in the brain.
Ptm:	Phosphorylation of Thr-69 and Thr-71 by MAPK14 causes increased transcriptional activity. Also phosphorylated and activated by JNK.
Similarity:	Belongs to the bZIP family. ATF subfamily.
Similarity:	Contains 1 bZIP domain.
Similarity:	Contains 1 C2H2-type zinc finger.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1 mg

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Delivery expected until 7/26/2024

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