Substance P (1-9)

GWB-26F02E

{ARG} {PRO} {LYS} {PRO} {GLN} {GLN} {PHE} {PHE} {GLY}

Tachykinins are active peptides which excite neurons evoke behavioral responses are potent vasodilators and secretagogues and contract (directly or indirectly) many smooth muscles.

Belongs to the tachykinin family. [1] Harmar A. J. Hyde V. and Chapman K. et al. Identification and cDNA sequence of delta-preprotachykinin a fourth splicing variant of the rat substance P precursor[2] Harmar A. J. et al. Direct Submission[3] Carter M. S. Krause J. E. Structure expression and some regulatory mechanisms of the rat preprotachykinin gene encoding substance P neurokinin A neuropeptide K and neuropeptide gamma. [4] Krause J. E. Chirgwin J. M. Carter M. S. Xu Z. S. Hershey A. D. Three rat preprotachykinin mRNAs encode the neuropeptides substance P and neurokinin A. [5] Kawaguchi Y. Hoshimaru M. Nawa H. Nakanishi S. Sequence analysis of cloned cDNA for rat substance P precursor: existence of a third substance P precursor. [6] Harmar A. J. Hyde V. Chapman K. E. Identification and cDNA sequence of delta-preprotachykinin a fourth splicing variant of the rat substance P precursor. [7] Chapman K. E. Lyons V. Harmar A. J. The sequence of 5\' flanking DNA from the rat preprotachykinin gene; analysis of putative transcription factor binding sites. [8] Khan I. Collins S. M. Fourth isoform of preprotachykinin messenger RNA encoding for substance P in the rat intestine. [9] McGregor G. P. Kage R. Thim L. Conlon J. M. Quantitation and characterization of peptides from the C-terminal flanking region of rat and bovine preprotachykinins.