IgA1


Item no.	25-783-72807
Manufacturer	GENWAY
Amount	1 ml
Category	Oncology Antibodies ELISA Secondary Antibodies By Organ Lymphatic System Cancer
Type	Antibody
Applications	ELISA
Clone	B3506B4
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-761A4A
Similar products	25-783-72807
Available
Genway ID:	GWB-761A4A
Specificity:	IgA1NCBI
Gene ID:	3493
Specificity:	IgA1
Clone:	B3506B4
Immunogen:	Human IgA1 heavy chains
Specificity Note:	This product recognises the Fc portion of the heavy chain of human IgA1 as demonstrated by ELISA.
Buffer Solution:	Phosphate buffered saline. pH7. 4
Preservative Stabilisers:		50% glycerol. Suggested
Dilution:	Suggested
Dilution:	ELISA - 1:500 - 1:2000
Function:	Ig alpha is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system.
Subunit:	Monomeric or polymeric.
Ptm:	3-Hydroxykynurenine an oxidized tryptophan metabolite that is common in biological fluids reacts with alpha-1-microglobulin to form heterogeneous polycyclic chromophores including hydroxanthommatin. The chromophore reacts with accessible cysteines forming non-reducible thioether cross-links with Ig alpha-1 chain C region Cys-352.
Disease:	A chromosomal aberration involving IGHA1 is found in multiple myeloma (MM) cell lines. Translocation t(1; 14)(q21; q32) that forms a FCRL4-IGHA1 fusion protein.
Similarity:	Contains 3 Ig-like (immunoglobulin-like) domains.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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