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THYROXINE

THYROXINE


Item no.	20-783-72859
Manufacturer	GENWAY
Amount	1 mg
Category	Antibodies ELISA Primary Antibodies
Type	Antibody
Applications	ELISA
Clone	BGN/098/281
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-D06AB0
Similar products	20-783-72859
Available
Genway ID:	GWB-D06AB0
Specificity:	THYROXINE
Specificity:	THYROXINE
Clone:	BGN/098/281
Immunogen:	Synthetic peptide corresponding to part of the native molecule conjugated to Bovine Serum Albumin.
Specificity Note:	T4 100%rT3 10%T3 1. 5%Cross reactivities determined at 10 nM analyte antibody at final dilution of 1/5K 250 ng of T4-KLH coated per well.
Preparation:	Purified IgG prepared by affinity chromatography on Protein A
Buffer Solution:	Phosphate buffered saline
Preservative Stabilisers:		0. 09% Sodium Azide (NaN3)
Function:	Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts.
Subunit:	Associates with LCK. Binds to HIV-1 gp120 and to P4HB/PDI and upon HIV-1 binding to the cell membrane is part of P4HB/PDI-CD4-CXCR4-gp120 complex. Interacts with HIV-1 Envelope polyprotein gp160 and protein Vpu. Interacts with Human Herpes virus 7 capsid proteins.
Subcellular Location:	Cell membrane; Single-pass type I membrane protein. Note=Localizes to lipid rafts. Removed from plasma membrane by HIV-1 Nef protein that increases clathrin-dependent endocytosis of this antigen to target it to lysosomal degradation. Cell surface expression is also down-modulated by HIV-1 Envelope polyprotein gp160 that interacts with and sequesters CD4 in the endoplasmic reticulum.
Ptm:	Palmitoylation and association with LCK contribute to the enrichment of CD4 in lipid rafts.
Miscellaneous:	Primary receptor for HIV-1.
Similarity:	Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
Similarity:	Contains 1 Ig-like V-type (immunoglobulin-like) domain.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1 mg

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Delivery expected until 8/30/2024

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