CD28


Item no.	20-783-72429
Manufacturer	GENWAY
Amount	100 TESTS
Category	Oncology Antibodies Flow Cytometry Primary Antibodies By Organ Heart & Blood Cancer
Type	Antibody
Applications	FC
Clone	YTH913. 12
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-6730EF
Similar products	20-783-72429
Available
Genway ID:	GWB-6730EF
Specificity:	CD28NCBI
Gene ID:	940
Specificity:	CD28
Clone:	YTH913. 12
Immunogen:	Human peripheral blood T-cells
Fusion Partner:	Spleen cells from an immunised DA rat were fused with cells of the Y3/Ag 1. 2. 3 rat myeloma cell line.
Specificity Note:	This product recognises the human CD28 cell surface antigen a 44kD glycoprotein expressed by a subset of T lymphocytes. It has been reported that this clone also recognises an epitope of CD28 expressed by NK cells which is not recognised by clones of 9. 3 or CD28. 2(1. ).
Preparation:	Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution:	Phosphate buffered saline pH7. 4
Preservative Stabilisers:		0. 09%Sodium Azide1%Bovine Serum Albumin Reconstitution: Reconstitute with 1 ml distilled waterSuggested
Flow Cytometry:	Use 10ul of the suggested working dilution to label 106 cells or 100ul human whole blood. Suggested
Dilution:	Flow Cytometry - Neat
Function:	Possibly involved in T-cell activation.
Subunit:	Homodimer; disulfide-linked. Interacts with DUSP14. Binds to CD80/B7-1 and CD86/B7-2/B70 (By similarity).
Subcellular Location:	Membrane; Single-pass type I membrane protein.
Similarity:	Contains 1 Ig-like V-type (immunoglobulin-like) domain. 1. Reiter. C. (1989) Cluster Report: CD28 in Leucocyte Typing IV: White Cell Differentiation Antigens. Edited by Knapp. W. . Dorken. B. . Gilks. W. R. . Rieber. E. P. . Schmidt. R. E. . Stein. H. and von dem Borne. A. E. G. Kr. Oxford University Press. pp 352-353. 2. Galea-Lauri. J. et al. (1999) Expression of a variant of CD28 on a subpopulation of human NK cells: Implications for B7-mediated stimulation of NK cells.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 TESTS

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