CD40


Item no.	20-783-70750
Manufacturer	GENWAY
Amount	100 TESTS
Category	Oncology Antibodies Flow Cytometry Primary Antibodies By Organ Heart & Blood Cancer
Type	Antibody
Applications	FC
Clone	LOB7/6
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-F06081
Similar products	20-783-70750
Available
Genway ID:	GWB-F06081
Specificity:	CD40NCBI
Gene ID:	958
Specificity:	CD40
Clone:	LOB7/6
Fusion Partner:	Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS1 myeloma cell line.
Specificity Note:	This product recognises the human CD40 cell surface antigen a 48kD glycoprotein expressed by B lymphocytes and weakly by some monocytes. CD40 is involved in the process of B cell selection in germinal centres and is vital in T cell-B cell interactions.
Buffer Solution:	Phosphate buffered saline pH7. 4
Preservative Stabilisers:		0. 09%Sodium Azide1%Bovine Serum Albumin Reconstitution: Reconstitute with 1ml distilled waterSuggested
Flow Cytometry:	Use 10ul of the suggested working dilution to label 106 cells in 100ul. Suggested
Dilution:	Flow Cytometry - Neat
Function:	Receptor for TNFSF5/CD40LG.
Subunit:	Interacts with TRAF3 and TRAF5. Interacts with TRAF1 TRAF2 and TRAF6 (By similarity).
Subcellular Location:	Isoform I: Cell membrane; Single-pass type I membrane protein.
Subcellular Location:	Isoform III: Cell membrane; Single-pass type I membrane protein.
Subcellular Location:	Isoform IV: Cell membrane; Single-pass type I membrane protein.
Subcellular Location:	Isoform V: Cell membrane; Single-pass type I membrane protein.
Subcellular Location:	Isoform II: Secreted.
Similarity:	Contains 4 TNFR-Cys repeats. 1. Quadbeck. B. et al. (2002) Maturation of thyroidal dendritic cells in Graves Disease. 2. Kirsch. B. M. et al . (2005) The active metabolite of leflunomide. A77 1726. interferes with dendritic cell function. Arthritis Res. Ther. 3. Cheadle. E. et al. (2003) Mycobacterium bovis bacillus Calmette-Guerin-infected dendritic cells potently activate autologous T cells via a B7 and interleukin-12-dependent mechanism. Immunology.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 TESTS

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Delivery expected until 8/30/2024

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