MOUSE ANTI METAPNEUMOVIRUS

METAPNEUMOVIRUS

Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

Recognises human metapneumovirus (hMPV) a member of the Paramyxoviridae RNA virus family. Metapneumovirus was discovered in 2001 and is distributed worldwide. Infection in the upper respiratory tract is associated with mild illness while lower respiratory tract infection can cause fever cough pneumonia bronchiolitis and wheezing. Severe lower respiratory tract infection is most common in the very young the very old and the immunosuppressed. Metapneumovirus is a common cause of respiratory infection. Phylogenetic analysis has shown two major genotypes A and B each containing two sub-divisions suggesting that four distinct lineages circulate in the population with different lineages predominating in different years.

Does not cross-react with cell cultures infected with hRSV influenzaviruses A and B adenovirus parainfluenza viruses 1 2 3 and 4b mumps virus measles virus varicella-zoster virus herpes simplex virus types 1 and 2 human cytomegalovirus human herpesvirus type 6 ECHOvirus 19 Coxsachievirus B4 poliovirus types 1-3 HHV6 or uninfected HeLa MA104 3MK LLC-MK HEp2 MRC-5 and HSB-2 cells. It also does not react with sputum bacteria. Recommended Secondary Antibodies: Rabbit Anti Mouse IgGGoat Anti Mouse IgGGoat Anti Mouse IgG (H/L)Goat Anti Mouse IgG IgA IgMHuCAL Anti Mouse IgG1Goat Anti Mouse IgG (Fc)Sheep Anti Mouse IgG (H/L) 1. Heiber M. et al (1996) A novel human gene encoding a G-protein-coupled receptor (GPR15) is located on chromosome 3. Genomics 32:462-5. 2. Deng H. K. et al (1997) Expression cloning of new receptors used by simian and human immunodeficiency viruses. Nature 388:296-300. 3. Farzan M. et al (1997) Two orphan seven-transmembrane segment receptors which are expressed in CD4-positive cells support simian immunodeficiency virus infection. J. Exp. Med. 186:405-11. [1] \" A novel human gene encoding a G-protein-coupled receptor (GPR15) is located on chromosome 3. \" Heiber M. Marchese A. Nguyen T. Heng H. H. Q. George S. R. O\' Dowd B. F. Genomics 32:462-465(1996) [PubMed: 8838812] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. [2] \" The status quality and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). \" The MGC Project TeamGenome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Liver.