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TPMT Antibody

TPMT Antibody

Item no.	20-614-460851
Manufacturer	GENWAY
Amount	0.1 ml
Category	Antibodies Flow Cytometry Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody
Applications	WB, FC, IHC
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-386B30
Similar products	20-614-460851
Available
Genway ID:	GWB-386B30
Immunogen:	Full length human recombinant protein of human TPMT (NP_000358) produced in HEK293T cell. Clone Name: clone 4C1
Isotype:	IgG1 Description: Homo sapiens thiopurine S-methyltransferase (TPMT)
Concentration:	0. 88 mg/ml Suggested
Dilutions:	WB 1:2000 IHC 1:50 Flow 1:100 This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals. A pseudogene for this locus is located on chromosome 18q.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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