BACE2


Item no.	18-783-76462
Manufacturer	GENWAY
Amount	0.1 mg
Category	Oncology Antibodies Western Blot Primary Antibodies By Organ Brain Cancer
Type	Antibody
Applications	WB
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-F99138
Similar products	18-783-76462
Available
Genway ID:	GWB-F99138
Specificity:	BACE2NCBI
Gene ID:	25825
Specificity:	BACE2
Immunogen:	Synthetic peptide corresponding to amino acids 44-59 of human BACE2. .
Specificity Note:	This product recognises an epitope within the N-terminal region of BACE2 a homologue of the beta-site APP cleaving enzyme (BACE). BACE2 has been reported to cleave the beta-amyloid precursor protein (APP) at the beta-site producing amyloid-beta protein (ABeta). Accumulation of ABeta plaques in the cerebral cortex play an important role in the pathogenesis of Alzheimer\' s disease particularly in individuals bearing the Flemish mutation.
Antiserum Preparation:	Antisera to human BACE2 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution:	Phosphate buffered saline
Preservative Stabilisers:		0. 02%Sodium Azide 1. Farzan. M. et al. (2000) BACE2. a beta -secretase homolog. cleaves at the beta site and within the amyloid-beta region of the amyloid-beta precursor protein.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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