RAGE

Item no.	18-783-76447
Manufacturer	GENWAY
Amount	0.1 ml
Category	Oncology Antibodies Immunohistochemistry ELISA Primary Antibodies By Organ Skin Cancer
Type	Antibody
Applications	IHC, ELISA
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-D5950B
Similar products	18-783-76447
Available
Genway ID:	GWB-D5950B
Specificity:	RAGENCBI
Gene ID:	177
Specificity:	RAGE
Immunogen:	Peptide corresponding to amino acids 42-59 of human RAGE.
Specificity Note:	This product recognises human Receptor for Advanced Glycation End products (RAGE). RAGE is a member of the Immunoglobulin superfamily which binds a variety of ligands including advanced glycation end products (AGEs) and amyloid fibrils. RAGE is expressed by endothelium mononuclear phagocytes smooth muscle and neurons. Recent studies suggest that RAGE may be involved in a range of pathological conditions including diabetes and Alzheimer\' s disease.
Immunohistology:	This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium Citrate buffer pH6. 0 is recommended for this purpose. Histology: Diabetic kidney
Antiserum Preparation:	Antisera to Human RAGE were raised by repeated immunisation of goats with highly purified antigen.
Preservative Stabilisers:		0. 09%Sodium Azide Summary: This protein is a member of the immunoglobulin superfamily of cell surface molecules. It is a receptor for various molecules including the amyloidogenic form of serum amyloid A amyloid-beta protein members of the S100/calgranulin superfamily and advanced glycation end products. The gene lies within the major histocompatibility complex (MHC) class III region on chromosome 6. Alternative splicing results in two transcript variants encoding different isoforms. 1. Schmidt. A. M. et al. (1996) RAGE: a novel cellular receptor for advanced glycation end products. Diabetes.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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