RABBIT ANTI ATG10

ATG10

Phosphate buffered saline

Synthetic peptide corresponding to a 15 aa sequence from near the carboxy terminus of human ATG10.

Plays a role in autophagy By similarity. ATG12-conjugating enzyme (E2-like enzyme) likely serves as an ATG5-recognition molecule. Subunit structureInteracts with MAP1LC3A. By interacting with MAP1LC3A it plays a role in the conjugation of ATG12 to ATG5. Also able to directly interact either with ATG5 or ATG7 By similarity. Subcellular locationCytoplasm Probable. Sequence similaritiesBelongs to the ATG10 family. Sequence cautionThe sequence BC004551 differs from that shown. Reason: Frameshift at position 26. The sequence BC027718 differs from that shown. Reason: Frameshift at position 26. 1. Wijdenes J. et al. (1995) Interleukin-6 signal transducer gp130 has specific binding sites for different cytokines as determined by antagonistic and agonistic anti-gp130 monoclonal antibodies Eur. J. Immunol. 25: 3474-3481. [1] \" Molecular cloning and expression of an IL-6 signal transducer gp130. \" Hibi M. Murakami M. Saito M. Hirano T. Taga T. Kishimoto T. Cell 63:1149-1157(1990) [PubMed: 2261637] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1) VARIANT VAL-8. Tissue: Myeloma and Placenta. [2] \" Cloning of novel soluble gp130 and detection of its neutralizing autoantibodies in rheumatoid arthritis. \" Tanaka M. Kishimura M. Ozaki S. Osakada F. Hashimoto H. Okubo M. Murakami M. Nakao K. J. Clin. Invest. 106:137-144(2000) [PubMed: 10880057] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2) VARIANT VAL-8. Tissue: Synovium. [3] Livingston R. J. Shaffer T. McFarland I. Nguyen C. P. Stanaway I. B. Rajkumar N. Johnson E. J. da Ponte S. H. Willa H. Ahearn M. O. Bertucci C. Acklestad J. Carroll A. Swanson J. Gildersleeve H. I. Nickerson D. A. Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databasesCited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. [4] Mural R. J. Istrail S. Sutton G. G. Florea L. Halpern A. L. Mobarry C. M. Lippert R. Walenz B. Shatkay H. Dew I. Miller J. R. Flanigan M. J. Edwards N. J. Bolanos R. Fasulo D. Halldorsson B. V. Hannenhalli S. Turner R. Yooseph S. Lu F. Nusskern D. R. Shue B. C. Zheng X. H. Zhong F. Delcher A. L. Huson D. H. Kravitz S. A. Mouchard L. Reinert K. Remington K. A. Clark A. G. Waterman M. S. Eichler E. E. Adams M. D. Hunkapiller M. W. Myers E. W. Venter J. C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databasesCited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. [5] \" Determination of the disulfide structure and N-glycosylation sites of the extracellular domain of the human signal transducer gp130. \" Moritz R. L. Hall N. E. Connolly L. M. Simpson R. J. J. Biol. Chem. 276:8244-8253(2001) [PubMed: 11098061] [Abstract]Cited for: PARTIAL PROTEIN SEQUENCE DISULFIDE BONDS GLYCOSYLATION AT ASN-43; ASN-83; ASN-131; ASN-157; ASN-227; ASN-379; ASN-383; ASN-553 AND ASN-564. [6] \" Dual oncostatin M (OSM) receptors. Cloning and characterization of an alternative signaling subunit conferring OSM-specific receptor activation. \" Mosley B. De Imus C. Friend D. Boiani N. Thoma B. Park L. S. Cosman D. J. Biol. Chem. 271:32635-32643(1996) [PubMed: 8999038] [Abstract]Cited for: SUBUNIT INDUCTION. [7] \" Phosphorylation of human gp130 at Ser-782 adjacent to the di-leucine internalization motif. Effects on expression and signaling. \" Gibson R. M. Schiemann W. P. Prichard L. B. Reno J. M. Ericsson L. H. Nathanson N. M. J. Biol. Chem. 275:22574-22582(2000) [PubMed: 10811661] [Abstract]Cited for: PHOSPHORYLATION AT SER-782 MUTAGENESIS OF SER-782 MASS SPECTROMETRY. [8] \" Human plasma N-glycoproteome analysis by immunoaffinity subtraction hydrazide chemistry and mass spectrometry. \" Liu T. Qian W. -J. Gritsenko M. A. Camp D. G. II Monroe M. E. Moore R. J. Smith R. D. J. Proteome Res. 4:2070-2080(2005) [PubMed: 16335952] [Abstract]Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-379 AND ASN-383 MASS SPECTROMETRY. Tissue: Plasma. [9] \" Global in vivo and site-specific phosphorylation dynamics in signaling networks. \" Olsen J. V. Blagoev B. Gnad F. Macek B. Kumar C. Mortensen P. Mann M. Cell 127:635-648(2006) [PubMed: 17081983] [Abstract]Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-667; SER-820 AND SER-829 MASS SPECTROMETRY. Tissue: Cervix carcinoma. [10] \" Phosphoproteome of resting human platelets. \" Zahedi R. P. Lewandrowski U. Wiesner J. Wortelkamp S. Moebius J. Schuetz C. Walter U. Gambaryan S. Sickmann A. J. Proteome Res. 7:526-534(2008) [PubMed: 18088087] [Abstract]Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-667 MASS SPECTROMETRY. Tissue: Platelet.