Asporin / ASPN

06-202-339712 - Immunizing Peptide

1-3ug/ml. Summary: ASPN belongs to a family of leucine-rich repeat (LRR) proteins associated with the cartilage matrix. The name asporin reflects the unique aspartate-rich N terminus and the overall similarity to decorin (MIM 125255) (Lorenzo et al. 2001 [PubMed 11152692]). [supplied by OMIM]. [1] Atif U. Philip A. Aponte J. Woldu E. M. Brady S. Kraus V. B. Jordan J. M. Doherty M. Wilson A. G. Moskowitz R. W. Hochberg M. et al. Absence of association of asporin polymorphisms and osteoarthritis susceptibility in US Caucasians[2] Poulou M. Kaliakatsos M. Tsezou A. Kanavakis E. Malizos K. N. and Tzetis M. Association of the CALM1 core promoter polymorphism with knee osteoarthritis in patients of Greek origin[3] Song J. H. Lee H. S. Kim C. J. Cho Y. G. Park Y. G. Nam S. W. Lee J. Y. and Park W. S. Aspartic acid repeat polymorphism of the asporin gene with susceptibility to osteoarthritis of the knee in a Korean population[4] Song Y. Q. Cheung K. M. Ho D. W. Poon S. C. Chiba K. Kawaguchi Y. Hirose Y. Alini M. Grad S. Yee A. F. Leong J. C. Luk K. D. et al. Association of the asporin D14 allele with lumbar-disc degeneration in Asians[5] Ikegawa S. et al. Expression regulation and function of asporin a susceptibility gene in common bone and joint diseases