RFLAT / KLF13

GWB-BB3F05

Peptide with sequence C-DASSPTISPASSP from the C Terminus of the Notes: Peptide ELISA: antibody detection limit dilution 1:4 000. Western Blot: Preliminary experiments gave no signal but low background in Jurkat and Molt-4 lysates at up to 1ug/ml. Summary: KLF13 belongs to a family of transcription factors that contain 3 classical zinc finger DNA-binding domains consisting of a zinc atom tetrahedrally coordinated by 2 cysteines and 2 histidines (C2H2 motif). These transcription factors bind to GC-rich sequences and related GT and CACCC boxes (Scohy et al. 2000 [PubMed 11087666]). [supplied by OMIM]. [1] Natesampillai S. Kerkvliet J. Leung P. C. and Veldhuis J. D. et al. Regulation of Kruppel-like factor 4 9 and 13 genes and the steroidogenic genes LDLR StAR and CYP11A in ovarian granulosa cells[2] Huang B. Ahn Y. T. McPherson L. Clayberger C. and Krensky A. M. et al. Interaction of PRP4 with Kruppel-like factor 13 regulates CCL5 transcription[3] Ahn Y. T. Huang B. McPherson L. Clayberger C. and Krensky A. M. et al. Dynamic interplay of transcriptional machinery and chromatin regulates \' late\' expression of the chemokine RANTES in T lymphocytes[4] Zhang P. Basu P. Redmond L. C. Morris P. E. Rupon J. W. Ginder G. D. and Lloyd J. A. A functional screen for Kruppel-like factors that regulate the human gamma-globin gene through the CACCC promoter element[5] Kanazawa A. Kawamura Y. Sekine A. Iida A. Tsunoda T. Kashiwagi A. Tanaka Y. Babazono T. Matsuda M. Kawai K. et al. Single nucleotide polymorphisms in the gene encoding Kruppel-like factor 7 are associated with type 2 diabetes