SCAP2 / PRAP

06-202-339124 - Immunizing Peptide

0. 5-2ug/ml. An additional band of unknown identity was also consistently observed at 28kDa. This band was successfully blocked by incubation with the immunising peptide. Summary: The protein encoded by this gene belongs to the src family kinases. This protein is similar to the src kinase associated phosphoprotein 1. It is an adaptor protein that is thought to play an essential role in the src signaling pathway in various cells. It inhibits PTK2B/RAFTK activity and regulates alpha-synuclein phosphorylation. [1] Harada T. Chelala C. Bhakta V. Chaplin T. Caulee K. Baril P. Young B. D. and Lemoine N. R. Genome-wide DNA copy number analysis in pancreatic cancer using high-density single nucleotide polymorphism arrays[2] Olsen J. V. Blagoev B. Gnad F. Macek B. Kumar C. Mortensen P. and Mann M. Global in vivo and site-specific phosphorylation dynamics in signaling networks[3] Barrios-Rodiles M. Brown K. R. Ozdamar B. Bose R. Liu Z. Donovan R. S. Shinjo F. Liu Y. Dembowy J. Taylor I. W. Luga V. et al. High-throughput mapping of a dynamic signaling network in mammalian cells[4] Park S. Y. Avraham H. K. and Avraham S. et al. RAFTK/Pyk2 activation is mediated by trans-acting autophosphorylation in a Src-independent manner[5] Takahashi T. Yamashita H. Nagano Y. Nakamura T. Ohmori H. Avraham H. Avraham S. Yasuda M. and Matsumoto M. Identification and characterization of a novel Pyk2/related adhesion focal tyrosine kinase-associated protein that inhibits alpha-synuclein phosphorylation