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CLCN6 (chloride channel 6)

CLCN6 (chloride channel 6)

Item no.	18-003-42643
Manufacturer	GENWAY
Amount	0.1 mg
Category	Oncology Antibodies Western Blot Primary Antibodies By Organ Uterine, Ovarian & Cervical Cancer
Type	Antibody
Applications	WB
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-4B2F0F
Similar products	18-003-42643
Available
Genway ID:	GWB-4B2F0F
Antigen Specificity:	Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human CLCN6.
ELISA Titre:	1:62500
Category:	Signaling Intermediates
Note:	Suggested starting concentrations are provided. Optimal dilutions should be determined by end-user. Differences in calculated versus apparent molecular weight may be due to post-translational modifications or protein hydrophobicity. The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7. Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. Chloride channel 6 and 7 belong to a subbranch
Function:	Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume; membrane potential stabilization signal transduction and transepithelial transport.
Subcellular Location:	Membrane; Multi-pass membrane protein.
Tissue Specificity:	Testis ovary small intestine brain and skeletal muscle. Low level expression in aortic and coronary vascular smooth muscle cells and aortic endothelial cells. Isoform C is only detected in kidney.
Similarity:	Belongs to the chloride channel (TC 1. A. 11) family [view classification].
Similarity:	Contains 2 CBS domains. Summary: The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7 Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. Chloride channel 6 and 7 belong to a subbranch of this family. Chloride channel 6 has four different alternatively spliced transcript variants. This protein is in close vicinity to two other kidney-specific chloride channel genes CLCNKA and CLCNKB. Tran. P. . et al. . (2002) Mamm. Genome 13 (9). 483-492.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1 mg

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