LHX3 (LIM homeobox 3)

Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human LHX3.

Suggested starting concentrations are provided. Optimal dilutions should be determined by end-user. Differences in calculated versus apparent molecular weight may be due to post-translational modifications or protein hydrophobicity. LHX3 encodes a member a large protein family which carry the LIM domain. a unique cysteine-rich zinc-binding domain. The encoded protein is a transcription factor that is required for pituitary development and motor neuron specification. Mutations in thisSummary: This protein is a member a large protein family which carry the LIM domain a unique cysteine-rich zinc-binding domain. The encoded protein is a transcription factor that is required for pituitary development and motor neuron specification. Mutations in this gene have been associated with a syndrome of combined pituitary hormone deficiency and rigid cervical spine. Two transcripts variants encoding distinct isoforms have been identified for this gene. Dattani. M. T. et al. . (2003) Endocrinol Metab 16 (9). 1207-1209.