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RAT ANTI MOUSE CD49b:FITC

RAT ANTI MOUSE CD49b:FITC

Item no.	20-783-315022
Manufacturer	GENWAY
Amount	0.02 mg
Category	Oncology Neuroscience Neural Adhesion Molecules Antibodies Primary Antibodies By Organ Bladder Cancer
Type	Antibody
Specific against	Mouse
Host	Rat
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-EE33EB
Similar products	20-783-315022
Available
Genway ID:	GWB-EE33EB
Specificity:	CD49b
Isotype:	IgM
Buffer Solution:	Phosphate buffered saline pH7. 4
Preservative Stabilisers:		0. 09% Sodium Azide 1% Bovine Serum AlbuminApprox. Protein Concentrations: IgM concentration 0. 1 mg/ml
Immunogen:	RIL-2 propogated NK1. 1+ cells from C57BL/6 mice.
Specificity:	Recognises mouse CD49b a 160kD cell surface antigen expressed by NK cells and a small subset of T-cells. Clone DX5 stains NK cells from all mouse strains tested including Balb/c mice.
Function:	Integrin alpha-2/beta-1 is a collagen receptor being responsible for adhesion of platelets and other cells to collagens modulation of collagen and collagenase gene expression force generation and organization of newly synthesized extracellular matrix. It is also a receptor for laminins collagen C-propeptides and E-cadherin. Mice homozygous for a null mutation in the alpha-2 die very early in embryogenesis. Subunit structureHeterodimer of an alpha and a beta subunit. Alpha-2 associates with beta-1. Interacts with HPS5 and RAB21. Ref. 3Subcellular locationMembrane; Single-pass type I membrane protein.
Domain:	The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage. Sequence similaritiesBelongs to the integrin alpha chain family. Contains 7 FG-GAP repeats. Contains 1 VWFA domain.

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Amount: 0.02 mg

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Delivery expected until 9/27/2024