Item no. |
Z03012-10 |
Manufacturer |
GenScript
|
Amount |
10 ug |
Category |
|
Type |
Proteins |
Specific against |
Human |
Purity |
> 95% by SDS-PAGE and HPLC analyses. |
Sequence |
Phe27-Phe217 (accession number: P01241). |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
protein/Z03012_10-Growth_Hormone_GH_Human,Growth Hormone (GH), is a member of the somatotropin/prolactin family which play an important role in growth control. The human GH cDNA encodes a 217 amino acid (aa), and the first 26 aa is a signal peptide. By alternative splicing, at least four isoforms of GH have been identified. The major role of GH in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. GH stimulates both the differentiation and proliferation of myoblasts, and also stimulates amino acid uptake and protein synthesis in muscle and other tissues. Recombinant, human Growth Hormone (rhGH), produced in, E. coli, is a single non-glycosylated polypeptide chain containing 191 amino acids. A fully biologically active molecule, rhGH has a molecular mass of 22.1 kDa analyzed by reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at GenScript.</td></tr><tr><th>M.W.</th><td colspan="7"> 22.1 kDa, observed by reducing SDS-PAGE.</td></tr><tr><th>Purity</th><td colspan="7"> > 95% by SDS-PAGE and HPLC analyses.</td></tr><tr><th>Endotoxin Level</th><td colspan="7"> < 0.2 EU/ug, determined by LAL method.</td></tr><tr><th>Specific Activity</th><td colspan="7"> ED50, 2.0× 106 units/mg.</td></tr><tr><th>Storage</th><td colspan="7"> Lyophilized recombinant, human Growth Hormone (rhGH), remains stable up to 6 months at -80C from date of receipt. Upon reconstitution, rhGH should be stable up to 2 weeks at 4C or up to 3 months at -20C.</td></tr><tr><th>Formulation</th><td colspan="7"> Lyophilized after extensive dialysis against PBS.</td></tr><tr><th>Reconstitution</th><td colspan="7"> Reconstituted in ddH2O at 100 ug/ml.</td></tr><tr><th>Sequence</th><td colspan="7"> Phe27-Phe217 (accession number: P01241).</td></tr><tr><th>Note</th><td colspan="7"> For research use only</td></tr> |
Similar products |
Growth |
Available |
|
Specificity |
ED50, 2.0x 106 units/mg. |
Specificity |
ED50, 2.0x 106 units/mg. |
Description |
Growth Hormone (GH), is a member of the somatotropin/prolactin family which play an important role in growth control. The human GH cDNA encodes a 217 amino acid (aa), and the first 26 aa is a signal peptide. By alternative splicing, at least four isoforms of GH have been identified. The major role of GH in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. GH stimulates both the differentiation and proliferation of myoblasts, and also stimulates amino acid uptake and protein synthesis in muscle and other tissues. Recombinant, human Growth Hormone (rhGH), produced in, E. coli, is a single non-glycosylated polypeptide chain containing 191 amino acids. A fully biologically active molecule, rhGH has a molecular mass of 22.1 kDa analyzed by reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at GenScript. |
Endotoxin Level |
< 0.2 EU/ug, determined by LAL method. |
Formulation |
Lyophilized after extensive dialysis against PBS. |
M.W. |
22.1 kDa, observed by reducing SDS-PAGE. |
Note |
For research use only |
Product Line |
Cytokines, Chemokines & Growth Factors |
Reconstitution |
Reconstituted in ddH2O at 100 ug/ml. |
Storage |
Lyophilized recombinant, human Growth Hormone (rhGH), remains stable up to 6 months at -80C from date of receipt. Upon reconstitution, rhGH should be stable up to 2 weeks at 4C or up to 3 months at -20C. |
Manufacturers Category |
Proteins |
Manufacturers Product Line |
Hormones |
Product Origin |
USA |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.