Comparison

IL-15, Human European Partner

Item no. Z00377-1
Manufacturer GenScript
Amount 1 mg
Category
Type Proteins
Specific against Human
Purity Greater than 98.0% as determined by: (a)Analysis by RP-HPLC (b)Anion-exchange FPLC (c)Analysis by reducing and non-reducing SDS-PAGE Silver Stained gel.
Sequence MNWVNVISDL KKIEDLIQSM HIDATLYTES DVHPSCKVTA MKCFLLELQV ISHESGDTDI HDTVENLIIL ANNILSSNGN ITESGCKECE ELEEKNIKEF LQSFVHIVQM FINTS
Citations Suzuki A, et al . Interleukin-15 increases hepatic regenerative activity. J. Hepatol. Sep 2006, 45 (3): 410-418. Lin SJ, et al . Effect of interleukin-15 on alloreactivity in umbilical cord blood. Transpl. Immunol. Aug 2006, 16 (2): 112-116. Waldmann TA. The biology of interleukin-2 and interleukin-15: implications for cancer therapy and vaccine design. Nat. Rev. Immunol. Aug 2006, 6 (8): 595-601.
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias protein/Z00377_1-Interleukin_15_IL_15_Human,Interleukin 15 (IL-15), is a cytokine that possesses a variety of biological functions. Interleukin 15 (IL-15) stimulates the proliferation of T-lymphocytes, which requires interaction of IL-15 with components of IL-2R, including IL-2R and probably IL-2R gamma, but not IL-2R. Recombinant human Interleukin 15 (IL-15), produced in, E. coli, is a single, non-glycosylated polypeptide chain containing 114 amino acids and having a molecular mass of 12,774 Da.</td></tr><tr><th>M.W.</th><td colspan="7"> 12,774 Da</td></tr><tr><th>Purity</th><td colspan="7"> Greater than 98.0% as determined by: (a)Analysis by RP-HPLC (b)Anion-exchange FPLC (c)Analysis by reducing and non-reducing SDS-PAGE Silver Stained gel.</td></tr><tr><th>Endotoxin Level</th><td colspan="7"> Less than 0.1 ng/ug (1 EU/ug) of recombinant human Interleukin-15 (IL-15) as determined by LAL test.</td></tr><tr><th>Specific Activity</th><td colspan="7"> The ED50 as determined by the dose-dependant stimulation of the proliferation of CTLL-2 was found to be <0.5 ng/ml, corresponding to a Specific Activity of 2x106 IU/mg.</td></tr><tr><th>Storage</th><td colspan="7"> Lyophilized, recombinant human Interleukin 15 (IL-15), remains stable at room temperature for three weeks, but it is best stored desiccated below -18C. Upon reconstitution recombinant human Interleukin 15 (IL-15) should be stored at 4C for up to seven days. For long term storage it is recommended that a carrier protein (0.1% HSA or BSA ) be added. Avoid repeated freeze-thaw cycles.</td></tr><tr><th>Formulation</th><td colspan="7">Recombinant human Interleukin-15 (IL-15), was lyophilized after extensive dialysis against 20mM PB, pH7.5, 150mM NaCl buffer.</td></tr><tr><th>Reconstitution</th><td colspan="7"> It is recommended to reconstitute the lyophilized, Recombinant Human Interleukin 15 (IL-15), in sterile 18 Momega-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.</td></tr><tr><th>Sequence</th><td colspan="7"> MNWVNVISDL KKIEDLIQSM HIDATLYTES DVHPSCKVTA MKCFLLELQV ISHESGDTDI HDTVENLIIL ANNILSSNGN ITESGCKECE ELEEKNIKEF LQSFVHIVQM FINTS </td></tr><tr><th>Reference</th><td colspan="7">Suzuki A, et al . Interleukin-15 increases hepatic regenerative activity. J. Hepatol. Sep 2006, 45 (3): 410-418. Lin SJ, et al . Effect of interleukin-15 on alloreactivity in umbilical cord blood. Transpl. Immunol. Aug 2006, 16 (2): 112-116. Waldmann TA. The biology of interleukin-2 and interleukin-15: implications for cancer therapy and vaccine design. Nat. Rev. Immunol. Aug 2006, 6 (8): 595-601.</td></tr>
Similar products Interleukin-15
Available
Specificity The ED50 as determined by the dose-dependant stimulation of the proliferation of CTLL-2 was found to be <0.5 ng/ml, corresponding to a Specific Activity of 2x106 IU/mg.
Specificity
The ED50 as determined by the dose-dependant stimulation of the proliferation of CTLL-2 was found to be <0.5 ng/ml, corresponding to a Specific Activity of 2x106 IU/mg.
Description
Interleukin 15 (IL-15), is a cytokine that possesses a variety of biological functions. Interleukin 15 (IL-15) stimulates the proliferation of T-lymphocytes, which requires interaction of IL-15 with components of IL-2R, including IL-2R and probably IL-2R gamma, but not IL-2R. Recombinant human Interleukin 15 (IL-15), produced in, E. coli, is a single, non-glycosylated polypeptide chain containing 114 amino acids and having a molecular mass of 12, 774 Da.
Endotoxin Level
Less than 0.1 ng/ug (1 EU/ug) of recombinant human Interleukin-15 (IL-15) as determined by LAL test.
Formulation
Recombinant human Interleukin-15 (IL-15), was lyophilized after extensive dialysis against 20mM PB, pH7.5, 150mM NaCl buffer.
M.W.
12, 774 Da
Product Line
Cytokine, Chemokines & Growth Factors
Reconstitution
It is recommended to reconstitute the lyophilized, Recombinant Human Interleukin 15 (IL-15), in sterile 18 Momega-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Storage
Lyophilized, recombinant human Interleukin 15 (IL-15), remains stable at room temperature for three weeks, but it is best stored desiccated below -18C. Upon reconstitution recombinant human Interleukin 15 (IL-15) should be stored at 4C for up to seven days. For long term storage it is recommended that a carrier protein (0.1% HSA or BSA ) be added. Avoid repeated freeze-thaw cycles.
Manufacturers Category
Proteins
Manufacturers Product Line
Cytokines
Product Origin
USA

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1 mg
Available: In stock
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