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PTP1B(PTPase)

PTP1B(PTPase)

Item no.	E1PA1S020
Manufacturer	Enogene
Amount	200ug/200ul
Category	Oncology Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Neural Signaling By Cell Type Carcinoma Peptides & Proteins Recombinant Proteins Stem Cell Markers
Type	Proteins
Specific against	other
Host	E.coli
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Available
Background	Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII- and p60c-src-induced signal transduction cascades. May regulate the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion. PTP1B is the prototype non-transmembrane PTP, originally identified in human placenta.
Research Area	Stem Cells, Cancer, Cardiovascular, Cell Biology, Epigenetics and Nuclear Signaling, Developmental Biologys, Immunology, Drug Discovery Products, Metabolism, Neuroscience, Signal Transduction
Form of Antibody	Liquid. The product is 1.0 mg/ml in 20mM HEPES, pH7.5, 100mM NaCl, 10mM beta-ME, 10% glycerol, 0.5mM EDTA.
Specificity/Sensitivity	ca.50 umol/min/mg at 30C using 0.15 mM of phosphopeptide substrate based on EGFR residues 988-998 in 50 mM HEPES, pH 7.2, 1 mM EDTA, 1 mM DTT, 0.05% NP-40, and 0.2 ug/ul bovine serum albumin.
Applications information	The protein is suitable for study tyrosine phosphatase kinetics and substrate specificity.
Source	Human protein tyrosine phosphatase (residues 1-322), expressed in E. coli.
Storage/Stability	Store at -20C. -80C for long-term storage. Avoid exposure to light. Avoid repeated freezing and thawing.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 200ug/200ul

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Delivery expected until 9/27/2024

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