Item no. |
E91046 |
Manufacturer |
Enogene
|
Amount |
100ul |
Category |
|
Type |
Antibody |
Applications |
Western Blot, Immunohistochemistry |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
U2AF1, DKFZp313J1712, FP793, RN, RNU2AF1, U2AF35, U2AFBP , |
Available |
|
Background |
U2 auxiliary factor (U2AF), comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. U2 (RNU2) small nuclear RNA auxiliary factor 1 (U2AF1, synonyms: RN, FP793, U2AF35, U2AFBP, RNU2AF1)is the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers. The U2AF1 gene is localized to chromosome 21q22.3, which is the critical region for three diseases, progressive myoclonus epilepsy, autoimmune polyglandular disease type 1, and one form of bipolar affective disorder. |
Research Area |
Autophagy antibody, Cancer, Cardiovascular, Cell Biology, Epigenetics and Nuclear Signaling, Developmental Biologys, Immunology, Drug Discovery Products, Metabolism, Neuroscience, Signal Transduction, Stem Cells |
Swiss-Prot No. |
Q01081 |
Altername |
U2AF1, DKFZp313J1712, FP793, RN, RNU2AF1, U2AF35, U2AFBP , |
Immunogen |
Recombinant protein of human U2AF1 |
Purification |
Affinity purification |
Applications information |
WB IHC |
Gene ID |
7307 WB 1:500 - 1:2000 IHC 1:50- 1:200 Western blot analysis of Colon320 cell andHela cell lysate using U2AF1 antibody. |
Molecular Weight |
28kDa |
Storage/Stability |
Store at -20C or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.