« Back
Home /
TRAF1 Antibody

TRAF1 Antibody

Manufacturer	Enogene
Category	Metabolism Diabetes Glucose Homeostasis Antibodies Western Blot Primary Antibodies
Type	Antibody
Specific against	Human, Mouse, Rat
Applications	Western Blot
Amount	100ul
Host	Rabbit
Item no.	E90150
eClass 6.1	32160702
eClass 9.0	32160702
Available
Alias	EBI6, MGC:10353,
Background	TRAF1 is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. TRAF1 and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV). EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins; this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors. TRAF1 is observed at 45-50 kDa in western blotting, and the additional bands of lower molecular weight (ca.30 kDa) may represent TRAF1 cleavage fragments, similar to the results obtained by the article (PMID:11098060).
Research Area	Autophagy antibody, Cancer, Cardiovascular, Cell Biology, Epigenetics and Nuclear Signaling, Developmental Biologys, Immunology, Drug Discovery Products, Metabolism, Neuroscience, Signal Transduction, Stem Cells
Swiss-Prot No.	Q13077
Altername	EBI6, MGC:10353,
Immunogen	Recombinant protein of human TRAF1
Purification	Affinity purification
Applications information	WB
Gene ID	7185 WB 1:500-1:2000
Molecular Weight	46kDa
Storage/Stability	Store at -20C or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

E90150-datasheet.pdf

Request safety datasheet

Simple Order Order Subscription

Amount: 100ul

available

Delivery expected until 8/23/2024

Express Delivery: Save 24 days

Compare

Add to wishlist

Recommend by mail