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UHRF1 Antibody

UHRF1 Antibody

Item no.	E90297
Manufacturer	Enogene
Amount	100ul
Category	Antibodies Western Blot Immunofluorescence Primary Antibodies
Type	Antibody
Applications	Immunofluorescence, Western Blot
Specific against	Human
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Np95, hNP95, ICBP90, RNF106, hUHRF1,
Available
Background	UHRF1, also named as ICBP90, NP95 and RNF106, is a putative E3 ubiquitin-protein ligase. It may participate in methylation-dependent transcriptional regulation. UHRF1 binds to inverted 5'-CCAAT-3' box 2 in the TOP2A promoter, and activates TOP2A expression. It is important for G1/S transition and may be involved in DNA repair and chromosomal stability. UHRF1's ability to repress its direct target gene expression is dependent on PHD(UHRF1) binding to unmodified H3R2.
Research Area	Autophagy antibody, Cancer, Cardiovascular, Cell Biology, Epigenetics and Nuclear Signaling, Developmental Biologys, Immunology, Drug Discovery Products, Metabolism, Neuroscience, Signal Transduction, Stem Cells
Swiss-Prot No.	Q96T88
Altername	Np95, hNP95, ICBP90, RNF106, hUHRF1,
Immunogen	Recombinant protein of human UHRF1
Purification	Affinity purification
Applications information	WB IF
Gene ID	29128 WB 1:500-1:2000 IF 1:20-1:50
Molecular Weight	91kDa
Storage/Stability	Store at -20C or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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