Comparison

GSK3 alpha Antibody

Item no. E10-20134
Manufacturer Enogene
Amount 100ug/100ul
Category
Type Antibody
Applications ELISA, Western Blot
Specific against Human
Host Mouse
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias DKFZp686D0638, GSK3A
Similar products GSK3 alpha
Available
Background
Glycogen synthase kinase 3 alpha belongs to the Ser/Thr family of protein kinases, Cdc2/cdkx subfamily, GSK3 subsubfamily. It is implicated in the hormonal control of several regulatory proteins including glycogen synthase, myb, and the transcription factor c jun. GSK3 phosphorylates glycogen synthase and thereby inactivates it. Insulin stimulates the dephosphorylation of glycogen synthase at the sites phosphorylated by GSK3 and subsequently inhibits GSK3 acutely leading to the stimulation of glycogen synthesis. GSK3 signaling is performed by two isoforms, GSK3 alpha and GSK3 beta. The two isoforms share 97% sequence similarity within their catalytic domains. GSK3 has also been shown to play a role in protein synthesis, cell adhesion, cell proliferation, cell differentiation, microtubule dynamics and cell motility.
Research Area
Autophagy antibody, Cancer, Cardiovascular, Cell Biology, Epigenetics and Nuclear Signaling, Developmental Biologys, Immunology, Drug Discovery Products, Metabolism, Neuroscience, Signal Transduction, Stem Cells
Form of Antibody
Ascitic fluid containing 0.03% sodium azide.
Altername
DKFZp686D0638, GSK3A
Immunogen
Purified recombinant fragment of GSK3 alpha expressed in E. Coli.
Applications information
WB, ELISA. Not yet tested in other applications. Determining optimal working dilutions by titration test.
Recommended Dilutions
WB:1/500 - 1/2000 , ELISA: Propose dilution 1/10000.
Storage/Stability
Store at 4C, for long term storage, store at -20C

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100ug/100ul
Available: In stock
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