Polyclonal KSHV ORF8 Antibody

Kaposi's sarcoma-associated herpesvirus (KSHV) belongs to the gamma-(2)-herpesvirus subfamily and has been closely linked to the Kaposi�s sarcoma, primary effusion lymphoma (PEL) and multicentric Castleman�s disease. The genome of KSHV is 165-170 kb and contains at least 88 open reading frames. KSHV ORF8 is a virion envelope-associated protein. Akula et al (2003) report it acts as a Glycoprotein B mediated signaling during virus entry. This Glycoprotein possesses the Arg-Gly-Asp (RGD) motif and utilizes alpha3beta1 integrin as one of the receptors for its entry into the target cells.

Rabbit anti-serum.

WB, ELISA. Not yet tested in other applications. Determining optimal working dilutions by titration test.

Store at 4C, for long term storage, store at -20C