Description of target |
Acts on phosphatidylinositol (PtdIns) in the first committed step in the production of the second messenger inositol-1, 4, 5, -trisphosphate.2 Publications
< p>Manually curated information for which there is published experimental evidence.< /p>
< p>< a href="/manual/evidences#ECO:0000269">Moreâa‚¬A< /a>< /p> Manual assertion based on experiment iniRef.3"Functional expression and characterisation of a new human phosphatidylinositol 4-kinase PI4K230."_x005F_x000D_ Gehrmann T., Guelkan H., Suer S., Herberg F.W., Balla A., Vereb G. Jr., Mayr G.W., Heilmeyer L.M.G. Jr._x005F_x000D_ Biochim. Biophys. Acta 1437:341-356(1999) [PubMed] [Europe PMC] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 59-2102 (ISOFORM 1), FUNCTION, CATALYTIC ACTIVITY, BIOPHYSICOCHEMICAL PROPERTIES, TISSUE SPECIFICITY.Ref.10"PtdIns4P synthesis by PI4KIIIalpha at the plasma membrane and its impact on plasma membrane identity."_x005F_x000D_ Nakatsu F., Baskin J.M., Chung J., Tanner L.B., Shui G., Lee S.Y., Pirruccello M., Hao M., Ingolia N.T., Wenk M.R., De Camilli P._x005F_x000D_ J. Cell Biol. 199:1003-1016(2012) [PubMed] [Europe PMC] [Abstract]Cited for: GENE STRUCTURE, FUNCTION, SUBCELLULAR LOCATION, IDENTIFICATION IN THE PI4K COMPLEX, ENZYME REGULATION. |