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Mouse sE-Selectin ELISA Kit EZ-Set™ (DIY Antibody Pairs) European Partner

Item no. BOS-EZ0502
Manufacturer Boster
Amount For 5 plates, 96 wells each, reagents only, plates are not included
Category
Type Elisa
Applications ELISA
Specific against Mouse
Sensitivity <10 pg/ml
ECLASS 10.1 32160605
ECLASS 11.0 32160605
UNSPSC 41116126
Alias E-selectin;CD62 antigen-like family member E;Endothelial leukocyte adhesion molecule 1;ELAM-1;Leukocyte-endothelial cell adhesion molecule 2;LECAM2;CD62E;Sele;Elam-1;
Available
Manufacturers Product Category
EZ-Set™ ELISA Kits (Ab Pairs)
Short Description
Mouse sE-Selectin ELISA Kit EZ-Set™ (DIY Antibody Pairs) (antibody pairs and standards for assay development). Quantitate Mouse SELE in cell culture supernatants, serum and plasma (heparin, citrate).
Description
Mouse sE-Selectin ELISA Kit EZ-Set™ (DIY Antibody Pairs) (antibody pairs and standards for assay development). Quantitate Mouse SELE in cell culture supernatants, serum and plasma (heparin, citrate).
Background
E-selectin, also called endothelial-leukocyte adhesion molecule-1 (ELAM-1), is a cell surface glycoprotein expressed by cytokine-activated endothelium that mediates the adhesion of blood neutrophils. An increased expression of E-selectin has been observed in the arterial endothelium interacting with lymphocytes and macrophages in human atherosclerotic lesions. E-selectin plays a critical role in mediating tissue-specific homing of T cells into skin, and of primitive hematopoietic progenitor cells (HPCs) into bone marrow (BM). A structurally and functionally related group of genes, lymph node homing receptor (LHR), granule membrane protein 140 (GMP-140), and endothelial leukocyte adhesion molecule 1 (ELAM-1) are shown to constitute a gene cluster on mouse and human chromosome 1. The standard product used in this kit is recombinant mouse E-Selectin, excluding intercellular E-Selectin and transmembrane domain. It consists of totally 557 amino acids with the molecular mass of 85.8KDa.
Gene Name
SELE
Immunogen
Expression system for standard: NS0; Immunogen sequence: W22-P557
Cross-reactivity
There is no detectable cross-reactivity with other relevant proteins.
Sample Type
cell culture supernatants, serum and plasma (heparin, citrate).
Storage
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
Anticoagulant
heparin or citrate
Gene Full Name
E-selectin
Molecular Weight
66750 MW
Protein Function
Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with PSGL1/SELPLG. May have a role in capillary morphogenesis.
Subcellular Localization
Cell membrane ; Single-pass type I membrane protein.
Protein Name
E-selectin
Sequence Similarities
Belongs to the selectin/LECAM family.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: For 5 plates, 96 wells each, reagents only, plates are not included
Available: In stock
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