Item no. |
E-AB-22086-200 |
Manufacturer |
Elabscience
|
Amount |
200uL |
Category |
|
Type |
Antibody Monoclonal |
Applications |
WB, IF |
Clone |
3C3 |
Specific against |
Human, Mouse, Rat |
Host |
Mouse |
Isotype |
IgG |
ECLASS 10.1 |
42030590 |
ECLASS 11.0 |
42030590 |
UNSPSC |
12352203 |
Alias |
HIST1H2BA, testis, bA317E16.3, H2B, H2B histone family member U, H2B histone family member U testis specific, H2B histone family, member U, (testis specific), H2B testis, H2B1A, H2BFU, H2BT, HIST1H2BA, Histone 1, H2ba, Histone cluster 1 H2ba, Histone H2B, |
Similar products |
Histone H2B, HIST1H2BA, TSH2B, Histone H2B type 1-A, testis, Testis-specific histone H2B, H2B, H2BFU, STBP, bA317E16.3, H2B histone family, member U, H2ba, H2B1A, Histone 1, H2B histone family member U, H2B histone family member U testis specific, (testis specific), H2B testis, H2BT, Histone cluster 1 H2ba, Histone H2B testis, Histone H2B type 1 A, Histone H2B type 1A, Testis specific histone H2B, TSH 2B, TSH2B.1 |
Available |
|
Research Areas |
Cancer, Epigenetics and Nuclear Signaling |
Synonyms |
HIST1H2BA, testis, bA317E16.3, H2B, H2B histone family member U, H2B histone family member U testis specific, H2B histone family, member U, (testis specific), H2B testis, H2B1A, H2BFU, H2BT, HIST1H2BA, Histone 1, H2ba, Histone cluster 1 H2ba, Histone H2B, Histone H2B testis, Histone H2B type 1 A, Histone H2B type 1-A, Histone H2B type 1A, STBP, Testis specific histone H2B, Testis-specific histone H2B, TSH 2B, TSH2B, TSH2B.1 |
Swissprot |
P33778 |
Background |
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. HIST1H2BB (Histone Cluster 1 H2B Family Member B) is a Protein Coding gene. Among its related pathways are DNA Double-Strand Break Repair and Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3. GO annotations related to this gene include sequence-specific DNA binding and protein heterodimerization activity. An important paralog of this gene is HIST1H2BN. |
Concentration |
1 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Synthetic Peptide |
Buffer |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
Purification Method |
Protein A purification |
Dilution |
WB 1:1000-3000, IF 1:100-200 |
Conjugation |
Unconjugated |
Calculated MW |
14kDa |
Observed MW |
14kDa |
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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.