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Phospho-Histone H3 (Ser10) Polyclonal Antibody

Phospho-Histone H3 (Ser10) Polyclonal Antibody

Manufacturer	Elabscience
Category	Oncology Antibodies By Cell Type Glioma Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies
Type	Antibody Polyclonal
Specific against	Human, Mouse, Rat
Isotype	IgG
Applications	WB, IF, ELISA, IHC-P
Amount	20uL
Host	Rabbit
Item no.	E-AB-20891-20
eClass 6.1	32160702
eClass 9.0	32160702
Available
Alias	HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD, HIST1H3F, H3FI, HIST1H3G, H3FH, HIST1H3H, H3FK, HIST1H3I, H3FF, HIST1H3J, H3FJ, Histone H3.1, Histone H3/a, Histone H3/b, Histone H3/c, Histone H3/d, Histone H3
Research Areas	Cancer, Epigenetics and Nuclear Signaling
Synonyms	HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD, HIST1H3F, H3FI, HIST1H3G, H3FH, HIST1H3H, H3FK, HIST1H3I, H3FF, HIST1H3J, H3FJ, Histone H3.1, Histone H3/a, Histone H3/b, Histone H3/c, Histone H3/d, Histone H3
Swissprot	P68431, Q71DI3, P84243
Background	Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Concentration	1 mg/mL
Storage	Store at -20C. Avoid freeze / thaw cycles.
Immunogen	Synthesized peptide derived from human Histone H3 around the phosphorylation site of Ser10
Buffer	PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification Method	Affinity purification
Dilution	WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000
Conjugation	Unconjugated
Calculated MW	15kDa
Observed MW	15kDa

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 20uL

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Delivery expected until 8/9/2024

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