Item no. |
E-AB-33393-20 |
Manufacturer |
Elabscience
|
Amount |
20uL |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB, ELISA |
Specific against |
Human |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Alpha-chymase, Chymase 1, Chymase 1 mast cell, chymase 1 preproprotein transcript E, chymase 1 preproprotein transcript I, Chymase, Chymase, heart, Chymase, mast cell, CMA1, CMA1, CYH, CYM, EC 3.4.21.39, Mast cell chymase 1, Mast cell protease 3, Mast cel |
Similar products |
MCT1, CMA1, heart, Chymase, CYM, CYH, MGC119890, MGC119891, chymase 1 preproprotein transcript E, chymase 1 preproprotein transcript I, mast cell, Alpha-chymase, Mast cell protease I, Mast cell protease 3, Mcpt5, Mast cell protease 5, Chymase 1, Chymase 1, Chymase 1 mast cell, EC 3.4.21.39, Mast cell chymase 1, Mast cell protease III, Mcp-5, MCP3P, MMCP-5 |
Available |
|
Research Areas |
Cancer, Cardiovascular, Immunology, Signal Transduction |
Synonyms |
Alpha-chymase, Chymase 1, Chymase 1 mast cell, chymase 1 preproprotein transcript E, chymase 1 preproprotein transcript I, Chymase, Chymase, heart, Chymase, mast cell, CMA1, CMA1, CYH, CYM, EC 3.4.21.39, Mast cell chymase 1, Mast cell protease 3, Mast cell protease 5, Mast cell protease I, Mast cell protease III, Mcp-5, MCP3P, Mcpt5, MCT1, MGC119890, MGC119891, MMCP-5 |
Swissprot |
P23946 |
Background |
This gene encodes a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and is thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Alternative splicing results in multiple variants.CMA1 (Chymase 1) is a Protein Coding gene. Diseases associated with CMA1 include Urticaria Pigmentosa and Urticaria. Among its related pathways are Degradation of the extracellular matrix and Agents Acting on the Renin-Angiotensin System Pathway, Pharmacodynamics. GO annotations related to this gene include serine-type endopeptidase activity and peptide binding. An important paralog of this gene is GZMB. |
Concentration |
1mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Synthesized peptide derived from the Internal region of human Chymase. |
Buffer |
PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4 |
Purification Method |
Affinity purification |
Dilution |
WB 1:500-1:2000, ELISA 1:20000 |
Conjugation |
Unconjugated |
Calculated MW |
27kDa |
Observed MW |
27kDa |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.