Recombinant Rat CLEC4D/CLECSF8 Protein (Fc Tag)

CLEC4D, Clecsf8, Mcl

A DNA sequence encoding the rat CLEC4D (Q69FH1) (Trp48-Lys218) was expressed with Fc region of human IgG1 at the N-terminus.

N-Fc

This product is provided as lyophilized powder which is shipped with ice packs.

< 1.0 EU per ug of the protein as determined by the LAL method

48.4 kDa

Lyophilized from sterile PBS, pH 7.4

C-type lectin (CLEC) family is a type of carbohydrate-binding protein domain named lectin. C-type lectins are the most diverse and prevalent lectin family in immunity with its requirement for calcium for binding. Proteins including a C-type lectin domain have diverse range of functions including cell-cell adhesion, immune response to pathogens and apoptosis. There are at least 14 types of C-type lectins: typeIto type?IV. CLEC4D(CLECSF8) is a typeII membrane glycoprotein belonging to the C-type lectin family, with restricted expression in the monocyte/macrophage lineage. It plays important roles in the function of macrophages.