Item no. |
ELS-PKSM041109-50ug |
Manufacturer |
Elabscience
|
Amount |
50ug |
Category |
|
Type |
Proteins |
Specific against |
Mouse |
Host |
Human Cells |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
Matrix metalloproteinase-9, MMP-9, 92 kDa gelatinase, 92 kDa type IV collagenase, Gelatinase B, GELB |
Similar products |
MMP-9, Matrix metalloproteinase-9, 92 kDa gelatinase, 92 kDa type IV collagenase, Gelatinase B, GELB |
Available |
|
Synonym |
Matrix metalloproteinase-9, MMP-9, 92 kDa gelatinase, 92 kDa type IV collagenase, Gelatinase B, GELB |
Storage |
< -20CC |
Protein Construction |
Recombinant Mouse Matrix Metalloproteinase-9 is produced by our Mammalian expression system and the target gene encoding Ala20-Pro730 is expressed with a 10His tag at the C-terminus. |
Sequence |
Ala20-Pro730 |
Fusion tag |
C-10His |
Accession |
P41245 |
Shipping |
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20CC. |
Purity |
> 95 % as determined by SDS-PAGE |
Endotoxin |
< 1.0 EU per ug as determined by the LAL method. |
Stability and Storage |
Store at < -20CC, stable for 6 months. Please minimize freeze-thaw cycles. |
Mol Mass |
80.2 kDa |
AP Mol Mass |
100 kDa |
Formulation |
Supplied as a 0.2 um filtered solution of 20mM Tris, 150mM NaCl, pH7.5 . |
Reconstitution |
Please refer to the printed manual for detailed information. |
Background |
Matrix metalloproteinases are a family of zinc and calcium dependent endopeptidases with the combined ability to degrade all the components of the extracellular matrix. MMP-9 (gelatinase B) can degrade a broad range of substrates including gelatin, collagen types IV and V, elastin and proteoglycan core protein. It is believed to act synergistically with interstitial collagenase (MMP1) in the degradation of fibrillar collagens as it degrades their denatured gelatin forms. MMP-9 is produced by keratinocytes, monocytes, macrophages and PMN leukocytes. MMP-9 is present in most cases of inflammatory responses. Structurally, MMP-9 may be divided into five distinct domains: a prodomain which is cleaved upon activation, a gelatinbinding domain consisting of three contiguous fibronectin type II units, a catalytic domain containing the zinc binding site, a prolinerich linker region, and a carboxyl terminal hemopexinlike domain. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.