Item no. |
ELS-PKSH033022-50ug |
Manufacturer |
Elabscience
|
Amount |
50ug |
Category |
|
Type |
Proteins |
Specific against |
Human |
Host |
Human Cells |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
Semaphorin-4D, A8,BB18, GR3, CD100,C9orf164,CD100,coll-4,M-sema-G,SEMAJ |
Similar products |
GR3, BB18, A8, CD100, SEMAJ, C9orf164, M-sema-G, coll-4, Semaphorin-4D |
Available |
|
Synonym |
Semaphorin-4D, A8, BB18, GR3, CD100, C9orf164, CD100, coll-4, M-sema-G, SEMAJ |
Storage |
according to manual |
Protein Construction |
Recombinant Human Semaphorin 4D is produced by our Mammalian expression system and the target gene encoding Met22-Arg734 is expressed with a 6His tag at the C-terminus. |
Sequence |
Met22-Arg734 |
Fusion tag |
C-6His |
Accession |
Q92854 |
Shipping |
This product is provided as lyophilized powder which is shipped with ice packs. |
Purity |
> 95 % as determined by reducing SDS-PAGE. |
Endotoxin |
< 1.0 EU per ug as determined by the LAL method. |
Stability and Storage |
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80CC. Reconstituted protein solution can be stored at 4-8C for 2-7 days. Aliquots of reconstituted samples are stable at < -20C for 3 months. |
Mol Mass |
80.2 kDa |
AP Mol Mass |
112 kDa |
Formulation |
Lyophilized from a 0.2 um filtered solution of 20mM PB; 150mM NaCl; pH 7.4. |
Reconstitution |
Please refer to the printed manual for detailed information. |
Background |
Semaphorin-4D is also known as A8; BB18; GR3; CD100. Semaphorin-4D belongs to the semaphorin family containing 1 Ig-like C2-type domain; 1 PSI domain and 1 Sema domain. It is the cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. It promotes the migration of cerebellar granule cells and of endothelial cells; regulates dendrite and axon branching and morphogenesis. Semaphorin-4D Plays a role in the immune system; Promotes signaling via SRC and PTK2B/PYK2; which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.